What kind of time problem does evolution have in terms of the half-life of the unstable components in living beings?
Submitted by on Sat, 04/07/2020 - 12:14
Dear Brother / Sister,
10.4.1-The Problem of Time in Evolution in terms of the Half-Life of Unstable Components in Living beings
Half-life is the time period required for a substance to be reduced to half the initial amount in chemical reactions.1
Although it is generally used for radioactive elements, it can also be used for all reacting compounds. Since the biochemical compounds are often degraded by the effect of the reactive components in the medium, a half-life of each biochemical compound can be mentioned.2
For example, RNA is a compound with a very short half-life in a laboratory environment. Therefore, effective precautions should be taken against chemicals that destroy RNA, and chemicals that destroy endogenous proteins showing nuclease activity should be added to isolation buffers. In addition, the test medium should have a certain temperature (0 to +4 ˚C) and acidity (pH; 7.2-8.5). Otherwise, the RNA degrades immediately, loses its stability and the experiment is wasted. This also applies to enzymes, coenzymes, other proteins and lipids involved. In fact, the same problem applies to some co-factors in mineral structure such as Fe+2, Cu+1 and Mn+2, which are involved in the enzyme structure because these elements react with oxygen in the air and become oxidized in a very short time; after that, they can no longer function as a co-factor.3
An experience I underwent in the laboratory
I can give an example of my experience in the laboratory regarding the issue. It is necessary to produce hydroxyl radicals (OH) to imitate the oxidative stress occurring in the cell in antioxidant activity determination tests. Fenton reactions are used for this. In other words, +2 valent iron (Fe+2), should break down hydrogen peroxide (H2O2) into hydroxyl radical. Hydrogen peroxide and dissolved iron chloride should be added to the test medium in order to do it.4
I prepared them and added them to the experiment medium, but I could not get the result I wanted. I did the experiment again and again but I could not succeed in doing it. It took 5 days. At the end of the 5th day, I realized that +2 valent iron (Fe+2) reacted with the oxygen in the air and became oxidized, that is, was converted to +3 valent iron (Fe+3) and became useless for this reaction. That is, it was necessary to add Fe+2 to the experiment medium as soon as I prepared it. However, I added this solution about half an hour after I prepared it. Thanks to this tiny but very important detail that I learned, I was able to do this experiment, which I could not accomplish in 5 days, in 5 minutes.
These unsuccessful experiments that I experienced helped me to notice a great operation. Yes, many reactions in living beings could not tolerate waiting. A successful biochemical reaction could take place only under certain conditions (temperature, concentration, pH, etc.) and at very short time periods.
Evolutionists’ claim that unstable compounds such as DNA, RNA and protein evolved under atmospheric conditions and in millions of years is contrary to the biochemistry of those molecules in the first place.
However, evolutionists mention longer times with exaggeration in order to increase the credibility of their claims in terms of time by ignoring this delicate issue in living beings. Nevertheless, there is a very important point that they miss; biological functioning has no tolerance to this extravagance. Evolutionists’ claim that unstable compounds such as DNA, RNA and protein evolved under atmospheric conditions and in millions of years is contrary to the biochemistry of those molecules in the first place.
1.E. Eden, N. Geva-Zatorsky, I. Issaeva, A. Cohen, E. Dekel, T. Danon, L. Cohen, A. Mayo, U. Alon, Proteome half-life dynamics in living human cells, Science (80-. ). (2011). doi:10.1126/science.1199784
2.E. et al. Eden, Proteome Half-Life Dynamics, Science (80-. ). (2011). doi:10.1126/science.1199784.
3.Y.S. Jung, W.T. Lim, J.Y. Park, Y.H. Kim, Effect of pH on Fenton and Fenton-like oxidation, Environ. Technol. (2009). doi:10.1080/09593330802468848.
4.J.J. Pignatello, E. Oliveros, A. MacKay, Advanced oxidation processes for organic contaminant destruction based on the Fenton reaction and related chemistry, Crit. Rev. Environ. Sci. Technol. (2006). doi:10.1080/10643380500326564.
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